Serum, Plasma

Melatonin Direct RIA

The Melatonin Direct RIA (BA R-3300) is a sensitive assay for the quantitative determination of Melatonin in human serum and plasma samples and is intended for in-vitro diagnosis and research applications.

Catalog Nr.: 
BA R-3300
Name: 

Melatonin Direct RIA

Description: 
Radioimmunoassay (RIA) for the quantitative determination of of Melatonin in serum and plasma
Design: 
Common sample preparation. 7 standards, 2 controls, ready for use. Double antibody technique.
Sample Volume: 
150 µl serum or plasma
Total Assay Time: 
Sample preparation 1 hour and RIA 20-24 hours
Standard Range: 

0 / 3 - 1 000 pg/ml

Sensitivity: 

2.3 pg/ml

Storage: 
2 - 8 °C
Kit: 
100 Determinations
Advantages: 
  • Direct assay
  • High specificity and sensitivity
  • 15 week shelf-life
  • Ready for use tracers
CE Mark: 
CE Marked

Melatonin in Serum and Plasma

In mammals, melatonin is biosynthesized in the pineal gland from the essential dietary amino acid tryptophan, with serotonin produced as an intermediate. In general Melatonin acts as an endocrine hormone.
Many biological effects of melatonin are generated through activation of melatonin receptors, while others are due to its role as a powerful antioxidant, being a direct scavenger of OH, O2−, and NO.
The serum and saliva melatonin levels in humans show a marked circadian rhythm characterized by very low levels during day time and high levels during night time.

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