Histamine Release

Histamine Release

In humans, Histamine acts predominantly on smooth muscle and blood vessels. It is responsible for the broncho-constriction occurring during the acute phase. In the vessels, its constrictive effect is limited to the venula, whereas arterioles are dilated. Furthermore, histamine causes a contraction of the cells of the vascular endothelium and increases the vascular permeability, thereby allowing higher-molecular substances to escape into the tissue.

In principle, heparinized whole blood samples are incubated with different concentrations of the suspected allergen. Release of histamine will occur upon stimulation of basophilic granulocytes depending on their sensibility to the allergen.
The histamine released in the supernatant is subsequently determined using a specific plasma immunoassay (Histamine ELISA; reference no. BA E-1000)

The Histamine Release kit (BA E-1100) is a supplementary kit for the quantitative determination of Histamine Release in heparinized whole blood.

Catalog Nr.: 
BA E-1100
Name: 

Histamine Release

Description: 
Supplementary kit for the quantitative determination of Histamine Release in heparinized whole blood.
Design: 
Supplementary kit for 96 determinations of Histamine Release. This kit has to be used in combination with the Histamine ELISA (BA E-1000).
Sample Volume: 
500 µl whole blood
Total Assay Time: 
Sample preparation 1.5 h
Standard Range: 

0 / 0.5 - 50 ng/ml

Sensitivity: 

Please inquire

Storage: 
2 - 8 °C
Kit: 
96 Determinations
Advantages: 

Please contact us.

CE Mark: 
CE Marked