Serum, Plasma, Urine and various biological samples

Serum, Plasma, Urine and various biological samples

Citrulline ELISA

Citrulline is a non-essential amino acid that is not incorporated into protein, and is present as
a free amino acid in most biological fluids such as plasma, urine and cerebrospinal fluid. It is
abyproduct of the enzymatic production of nitric oxide from the amino acid arginine and can
be used as a surrogate marker for the NO synthesis.
Elevated NO synthesis plays a significant role in inflammatory processes and has been
implaced in several autoimmune disorders.
The metabolism of citrulline is mainly divided between the intestine (synthesis) and the kidneys (degradation). Because of this specificity, citrulline can act as a reliable functional marker for these two organs. Severe renal failure (especially of the proximal tubules) is characterized by hypercitrullinaemia.
LDN has developed an Enzyme-Linked Immunosorbent Assay (ELISA) which is useful for
measuring Citrulline levels under different healthy and pathological conditions. The assay
characteristics were established for the use of serum, plasma, urine and many other different kinds of biological samples.

ELISA – Kit Catalog Details

Citrulline ELISA

BA E-2800 show more