Metanephrine and Normetanephrine in Urine

Metanephrine and Normetanephrine in Urine

Urinary Metanephrines
Metanephrine and normetanephrine are the 3-methoxy metabolites of epinephrine and norepinephrine, respectively. They are metabolized to vanillylmandelic acid or excreted with the urine.
Patients with pheochromocytoma or other tumours derived from neuroendocrine cells show elevated urinary levels of total Metanephrines.
As catecholamine secretion from neuroendocrine cells might show high variations urine samples collected over a period of 24 hours are used to average these fluctuations.

This group of assays is intended for the fast measurement of metanephrine and/or normetanephrine in urine samples.
Using a simple hydrolysis step the total metanephrine and normetanephrine can be quantified.

The assays show the following common features:

  • speed and ease of use
  • for in-vitro diagnostic and research applications
  • wide standard ranges
  • the ELISA is automatable
  • freedom from drug interferences
  • excellent correlation with HPLC
  • single and multi parameter kits available

Products

ELISA – Single Parameter KitsCatalogue No.Details
Metanephrine Urine ELISA Fast TrackBA E-8400show more
Normetanephrine Urine ELISA Fast TrackBA E-8500show more
ELISA –   Multi Parameter KitsCatalogue No.Details
2-MET Urine ELISA Fast TrackBA E-8600show more