Serotonin Research ELISA
Serotonin (5-hydroxytryptamine) belongs to the group of biogenic amines and is an intermediate product of the tryptophan metabolism. It plays an important role as a neurotransmitter in the regulation of different behavioral patterns such as motor activity, aggression, sexuality, appetite, and sleep.
Diseases which are associated with altered serotonin concentrations include disorders of the CNS, for example autism, epilepsy, schizophrenia and depression, and carcinoid tumors ot the intestine or bronchi.
The Serotonin Research ELISA offers a flexible protocol which is suitable for the high-sensitive quantitative measurement of Serotonin in any biological sample such as tissue homogenates, cell culture supernatant, cerebrospinal fluid (CSF), platelet-poor-plasma, and cell lysates.
There is an increasing interest to elucidate the important roles catecholamines play in development, cardiovascular function, psychiatric disorders and behaviour, neurodegenerative diseases, sleep, mood, attention, learning and metabolism.
Research in these areas often requires sensitive and flexible methods which are able to quantify minute amounts of analytes – methods, which give reliable results even using the smallest sample volume.
The following group of Research ELISAs™ is designed for the high-sensitive quantification of Epinephrine (Adrenaline), Norepinephrine (Noradrenaline) or Dopamine. Any kind of biological sample can be used with a minimal sample volume as low as 1 µl. The assay sensitivities depend on sample volume – reaching the highest sensitivity with 750 µl of sample volume.
Reported applications comprise different kinds of tissue homogenates (e.g. brain homogenates), micro-dialysates, cell culture, and many other biological samples.
Please don’t hesitate to contact our lab specialists to establish your custom-made protocol.
The assays show the following common features:
- High sensitivity
- Small sample volumes
- Flexible protocols
- Designed to test various sample types from multiple species
- Elegant and efficient extraction method
- Freedom from drug interferences
- Single and multi parameter kits available
Any biological fluid/sample
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